New study for Men with Lower Urinary Tract Symptoms
20 March, 2017
Bladder Health UK are always willing to give our support as a Patient Organisation to worthwhile research programmes. We have worked with study groups in Newcastle upon Tyne over several years and are really happy to help. We have been asked to approach our male members and or other potential candidates in the North East of England with a view to them taking part in a new study into primary care management of urinary tract symptoms - PriMUS. If you would be interested, please contact Bladder Health UK for further details including details of the honorairium payable.’
PriMUS PPI lay summary
Primary care Management of lower Urinary tract Symptoms in men: Development and validation of a diagnostic and decision-making aid. We are seeking two male PPI representatives based in the North East of England (preferably Newcastle upon Tyne) to join the study management group for our PriMUS study which will run for 3 years from May 2017. The PPI activities involved are described in a separate document available form the study group. This document provides a lay summary of the study:
More than 10% of older men experience the need to pass urine more frequently than usual and often find their sleep interrupted by having to go to the toilet at night. Some will find that their urine flow rate has become slower, and some will experience loss of bladder control. Such problems are distressing for men and are a common reason why men visit a general practitioner (GP), with over 60,000 attendances yearly across the UK. They firstly need reassurance that they are not suffering from cancer or any other sinister medical condition. GPs follow established procedures when considering signs of cancer or these more serious conditions, but they have no easily available assessment tools to identify other more common causes of lower urinary tract symptoms (LUTS), or to advise men about the best treatment options for symptom relief.
Because of this, men have to be referred to hospital based urology specialists for tests and diagnosis. We aim to establish a practical and accurate decision aid for use by GPs to diagnose the cause of LUTS in men and to assist decisions in determining appropriate person-centred treatment. Success of the study will benefit men with LUTS, general practice and the wider health system by:
- Reducing waiting times before men are assessed and diagnosed
- Giving men early access to appropriate treatment plans personalised to them
- Reducing the number of men needing referral to hospital based urology specialists
- Early referral of those men with more complex problems to specialist urology services
The study will demonstrate if a set of simple test results can be incorporated into a computer software programme for use by GPs to establish a diagnosis of the cause of LUTS in an individual and therefore guide selection of appropriate treatment options to relieve symptoms. With the help of general practices across the UK, we will recruit 880 men with LUTS into the study. The tests will include men keeping a diary for a few days to record the timing and amount of urine passed, measuring urine flow with a small portable machine, and asking men to complete symptom questionnaires. To assess the performance and accuracy of the tests, all men in the study will also need to have a more complicated test done by a specially trained nurse. This special test is called urodynamics and involves the passing of a thin tube into the bladder through which the bladder is then filled with water. A thin rectal catheter is also needed to control for changes in abdominal pressure. By comparing results of the simple tests with results of urodynamics we will identify which simple tests give best agreement. The top performing simple tests will then be incorporated into development of the decision making aid. The decision aid will be presented to GPs in a format that allows them to enter test results and then get a read out of the diagnosis and recommended treatment. The study will also consider practicalities for both patients and clinical staff in doing the simple tests in the general practice setting, and the ease with which the decision making tool can be used. The study is being run by Cardiff University in collaboration with other groups around the UK.
BHUK is working with Alison ( see below) to seek out willing candidates to assist with this valuable study.
Alison Bray, Clinical Scientist (pre-reg),
Medical Physics, Newcastle upon Tyne Hospitals NHS Foundation Trust,
RVI, Newcastle upon Tyne, NE1 4LP.